scholarly journals Dna flow cytometry and pathologic grading as prognostic guides in axillary lymph node-negative breast cancer

Cancer ◽  
1993 ◽  
Vol 72 (6) ◽  
pp. 1926-1932 ◽  
Author(s):  
Douglas E. Merkel ◽  
David J. Winchester ◽  
Robert A. Goldschmidt ◽  
Carey Z. August ◽  
Debra M. Wruck ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Flow Cytometry ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Dna Flow Cytometry ◽  
Axillary Lymph ◽  
Node Negative ◽  
Node Negative Breast Cancer

The prognosis of HER2/neu expression in axillary lymph node-negative breast cancer patients

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 9653-9653
Author(s):  
G.-H. Di ◽  
H.-C. Li ◽  
Y.-F. Hou ◽  
J.-S. Lu ◽  
J. Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Node Negative ◽  
Node Negative Breast Cancer

The prognosis of HER2/neu expression in axillary lymph node-negative breast cancer patients

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 9653-9653
Author(s):  
G.-H. Di ◽  
H.-C. Li ◽  
Y.-F. Hou ◽  
J.-S. Lu ◽  
J. Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Node Negative ◽  
Node Negative Breast Cancer

scholarly journals The Significance of Micrometastasis in Axillary Lymph Node Negative Breast Cancer

2000 ◽  
Vol 3 (1) ◽  
pp. 16
Author(s):  
Jang Yong Kim ◽  
Joo Whan Jeong ◽  
Sei Joong Kim ◽  
Sun Keun Choi ◽  
Ze Hong Woo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Node Negative ◽  
Node Negative Breast Cancer

scholarly journals Immunohistochemical detection of axillary lymph node micrometastases in node negative breast cancer patients using cytokeratin and epithelial membrane antigen

2015 ◽  
Vol 04 (01) ◽  
pp. 028-031 ◽  
Author(s):  
Monisha Choudhury ◽  
Sapna Agrawal ◽  
Mukta Pujani ◽  
Shaji Thomas ◽  
Meenu Pujani
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Axillary Lymph Node ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Node Negative ◽  
Occult Metastases ◽  
Node Negative Breast Cancer ◽  
Node Metastases

Abstract Background and Objective: The study was conducted to detect occult metastases in lymph node negative breast cancer patients using cytokeratin (CK) and epithelial membrane antigen (EMA) immunohistochemistry (IHC) and correlate this with primary tumor size and grade. Materials and Methods: A total of 32 cases including 12 prospective and 20 retrospective cases of axillary lymph node negative breast cancer were studied. CK and EMA IHC were performed to detect micrometastases. Results: Axillary lymph node metastases were detected in 18.75% of previously node negative cases using CK and EMA IHC. CK was found to be more sensitive for detection of metastases compared to EMA. A highly significant correlation was observed between tumor grade and axillary lymph node metastases detected by CK and EMA. However, no significant correlation was found between tumor size and axillary lymph node metastases detected by IHC. Conclusion: In the present study, there was an increase of 18.75% in the occult metastases detection rate using CK and EMA. To conclude, IHC detection of occult metastases should be done using CK in all axillary node negative cases, especially in T1 and T2 stage tumors.

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